http://breast-cancer-research.com/content/10/5/R83/comments The latest comments on the article 'Recurrence dynamics does not depend on the recurrence site' 2008-11-13T14:41:09Z http://breast-cancer-research.com/content/10/5/R83/comments#313635 <p>The phenomenon described by the authors is known as bi-modal hazard rate (BMH).In an detailed analysis based of SEER data I have shown that hazard rate in breast cancer proceeds through three phases. Following diagnosis and treatment hazard rate rises (AB). By the third year it reaches its maximum whereupon it declines to a minimum (BC). from there and on it gradually rises to a second maximum whereupon the patient dies (CD). This pattern appears in many cancers and is unique to cancer and does not appear in other chronic diseases. It is an epidemiological hallmark of cancer. It is so typical of cancer that it distinguishes cancer from other chronic diseases.</p><p>http://www.what-is-cancer.com/papers/newmedicine/epidemiologyFrame.htm</p><p>Data source: Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER*Stat Database: Incidence - SEER 9 Regs Public-Use, Nov 2004 Sub (1973-2002), National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch, released April 2005, based on the November 2004 submission.</p><p>More in </p><p>http://www.what-is-cancer.com/papers/newmedicine/epidemiologyFrame.htm</p> Gershom Zajicek 2008-11-13T14:41:09Z http://breast-cancer-research.com/content/10/5/R83 Demicheli et al. Breast Cancer Research 10 R83 Thu Oct 09 00:00:00 BST 2008